In an unprecedented large-scale study, researchers have mapped out the first molecular events that cause harmful protein buildups in the brain of people with Alzheimer's disease. "By measuring the ...

After studying 140,000 versions of the Aβ42 peptide, scientists identified some of the earliest molecular interactions that drive the formation of harmful amyloid protein aggregates found in Alzheimer ...

A new study suggests that two of Alzheimer’s disease’s most debated players may be more closely connected than they first ...

Can mirror proteins cure Alzheimer's? Scientists used "right-handed" amino acids to trap amyloid-beta proteins. This breakthrough in molecular recognition offers a new way to target "undruggable" ...

Researchers found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid formation by hen egg white lysozyme, a-synuclein, amyloid b 1-40, and b2-microglobulin. The high ...

Beta-amyloid plaques are considered a hallmark of Alzheimer’s disease, but they’re not the sole cause of the disease and its symptoms. Alzheimer’s is a complicated disease that experts are still ...

Devastating neurodegenerative diseases like Huntington's, Alzheimer's, and Parkinson's are all associated with protein deposits in the brain, known as amyloid. Despite extensive research investment ...

Researchers from Osaka University find that peristaltic pump action and high shear flow forces promote amyloid nucleation. The factor that tips you over the edge from being at risk for a disease to ...

Piller is an investigative journalist for Science. In November 2022, Dennis Selkoe, a Harvard professor of neurologic diseases and among the most celebrated and prolific Alzheimer’s researchers, ...