Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

EM, researchers showed that water mediates catalysis and important protein interactions for RNA polymerase II function in ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...

RNA polymerase, the enzyme that synthesizes RNA from DNA during transcription, has been captured mid-reaction for the first ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Researchers use AI to discover 14 distinct nucleosome states, revealing that DNA packaging acts as a "volume dial" for gene ...

Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the ...

Studies have shown that certain DNA variants have been linked to specific health conditions. But whether they can act as a ...