Epigenetic regulation comprises heritable changes in gene activity that do not alter the underlying DNA sequence, and plays a central role in orchestrating plant developmental programmes. Key ...

Epigenetic regulation in colorectal cancer encompasses heritable alterations in gene expression without changes to the underlying DNA sequence. Principal mechanisms include DNA methylation at CpG ...

Epigenetic clocks are important tools in modern aging research. Typically, they use characteristic DNA methylation patterns ...

This review is designed by Dr. Yinglan Zhao and written by her PhD students Dr. Lei Tao and Yue Zhou (Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University).

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

For decades, biology textbooks and popular science writing told a clean story: feed a honeybee larva royal jelly, and it ...

Epigenetics, a term coined by Conrad H. Waddington in the early 1940s, originally described the complex molecular pathways that govern how a genotype manifests as a phenotype. Over time, this ...

Researchers at Karolinska Institutet in Sweden and Kyoto University in Japan have identified new subgroups of the blood ...

Epigenetics is a rapidly growing field of study that focuses on the heritable changes in gene expression that occur without alterations to the underlying DNA sequence. These changes are caused by ...

Image Caption: Epigenetic regulation of receptors. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

What parents experience before conception and during pregnancy can leave a lasting impact on offspring brain development. Maternal factors, including ...