Charitharth Vivek Lal, M.D., and University of Alabama at Birmingham colleagues have used a novel and first-of-its-kind newborn mouse model to study the effect of high oxygen concentrations, or ...

The impact of caffeine on NETs secretion in neutrophils triggered by hyperoxia-induced A549 cells was examined. The role of the IL-8/CXCR2 axis in inducing NETs was evaluated using IL-8 and anti-CXCR2 ...

Oxidative and inflammatory stimuli encountered after preterm birth injure the immature lung and contribute to the pathogenesis of bronchopulmonary dysplasia (BPD) (1). Strategies aimed at preventing ...

This study confirms what many emergency medicine and critical care physicians have suspected for a long time -- that unnecessarily high concentrations of arterial oxygen may contribute to worse ...

Extreme hyperoxia was associated with less favorable short-term neurologic outcomes in patients who underwent extracorporeal membrane oxygenation (ECMO)-assisted cardiopulmonary resuscitation (ECPR) ...

Researchers have used a novel and first-of-its-kind newborn mouse model to study the effect of high oxygen concentrations, or hyperoxia, on lung development of newborn mice that are germ-free -- ...

Patients who have excessive oxygen levels in arterial blood (hyperoxia) following resuscitation from cardiac arrest have a higher rate of death in the hospital than similar patients without arterial ...

Researchers at the Hennepin County Medical Center, University of Minnesota, and Minneapolis Medical Research Foundation (Minneapolis, Minnesota) report that the combined use of hyperbaric oxygen and ...

When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, ...

Perinatal hyperoxia in preterm infants is associated with several well-known sequelae, including bronchopulmonary dysplasia and retinopathy of prematurity. Hyperoxia also induces alterations in ...