De-escalating immune checkpoint blockers (ICBs) in non-small cell lung cancer (NSCLC) by cutting the dose, duration, and frequency of administration could optimize treatment efficacy, reduce ...

Immune checkpoint inhibitors are a form of cancer immunotherapy successfully used to treat a wide range of cancers. However, ...

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar ...

Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing. This ...

Recent Publication and Growing Industry Focus on Immune-Priming Strategies Support Continued Evaluation of Gedeptin(R) as a ...

ICIs combined with chemotherapy showed higher efficacy than bevacizumab in treating advanced driver gene–negative NS-NSCLC. The study reported improved PFS and OS for patients receiving ICIs compared ...

Colon cancer hides from the immune system via one gene. University of Calgary researchers deleted it in mice, eradicating 100 ...

Adverse events profile of novel agents targeting immune checkpoints beyond PD-1/PD-L1 and CTLA-4 in solid tumors: A meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.

MSI-H mCRC patients receiving ICIs had significantly improved OS compared to chemotherapy, with a 63% improvement in survival. MSS patients with high albumin levels or recent antibiotic use also ...

Hepatocellular carcinoma (HCC) accounts for over 80% of all primary liver cancers and is the fourth leading cause of cancer death worldwide 1. HCC’s rise in recent years may be driven by the rise in ...

Immune checkpoint inhibitors have transformed the management of advanced malignancies by releasing the brakes on antitumour T-cell responses. Agents targeting programmed cell death protein 1 (PD-1), ...

When immune checkpoint inhibitors are used in cancer treatment, in some cases it can lead to severe inflammation and damage to heart tissue. Histology images of mouse heart tissue illustrate the ...