Microbial activity underpins numerous processes in natural, industrial and clinical systems. Isothermal calorimetry has emerged as a sensitive, non-invasive technique to quantify the metabolic heat ...
Biochemical reactions are regulated by enzymes. These reactions involve binding, recognition, and the creation of non-covalent complexes. It is essential to characterize binding events in order to ...
Complexes, such as protein/protein, nucleic acids/nucleic acid, protein/nucleic acid, protein/ligand, nucleic acid/ligand, are often difficult to crystallize even on well-defined biological systems, ...
The goal of this study is to use the model system described earlier to make direct measurements of the enthalpy of helix formation at different temperatures. For this we studied model alanine peptides ...
Please acknowledge the SIP core facility ( RRID: SCR_018986) in publications, on posters, or in talks if you use any instruments in the SIP core facility. Please include SIP's RRID (RRID: SCR_018986) ...
MicroCal has introduced the new iTC200 Isothermal Titration Calorimeter using which researchers can achieve gold standard binding affinities with only 200 µl of sample. The iTC200 determines all ...
Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...
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