This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

Lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells. Cancer cells have a unique ...

Discover how CKMT2 controls energy balance and mitochondrial health in skeletal muscles, revealing a new link between metabolism and type 2 diabetes management. Study: Decreased mitochondrial creatine ...

Glucagon is a pancreatic hormone that plays a crucial role in regulating glucose and whole-body energy metabolism. In individuals with diabetes, the pancreatic alpha cells that produce glucagon are ...

In the increasingly personalized world of nutrition science, metabolic typing has emerged as an intriguing approach that suggests a one-size-fits-all diet is fundamentally flawed. This system proposes ...

image: Bioengineers from the University of California, San Diego developed an explanation for why some types of neurons die sooner than others in the brains of people with Alzheimer’s disease. These ...

Glucolipid metabolism is a core biological process for maintaining energy balance and homeostasis in the human body. However, the widespread adoption of ...

Those with Type 1 diabetes (T1D) have higher glucagon levels right after eating than healthy individuals, but the reason why had not been determined. Using a novel glucagon isotope tracer, UAB ...