Rheumatoid arthritis (RA) is a chronic autoimmune condition that causes inflamed joints with pain, swelling, stiffness, and reduced range of motion. It most often affects women. Symptoms may come and ...

Methotrexate falls into the category of disease-modifying antirheumatic drugs, or DMARDs. These drugs do more than deal with symptoms; they actually slow down progression of the disease. About 60 ...

Methotrexate, sold under the brand name Methoblastin, is an antifolate drug, which means it inhibits the activation of folic acid in the body. It is taken once per week to treat a range of conditions.

Methotrexate shows good efficacy in a proportion of patients: 40% of treated patients with rheumatoid arthritis achieve an ACR50 response The mechanism of action of methotrexate has not fully been ...

Few blinded trials have compared conventional therapy consisting of a combination of disease-modifying antirheumatic drugs with biologic agents in patients with rheumatoid arthritis who have active ...