We then sought to resolve the structure of the Sre1-Scp1 complex, as well as the individual components. Despite rigorous trials, these proteins defied our crystallization efforts. To solve this ...
Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Sterol regulatory element-binding protein (SREBP) transcription factors are master regulators of cellular lipid homeostasis in mammals and oxygen-responsive regulators of hypoxic adaptation in fungi.
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