Researchers reveal TGF-β1 promotes scar tissue formation and restricts recovery ...

In a recent study published in Scientific Reports, researchers reported that microfibril-associated protein 5 (MFAP5) mediates wound healing through its pro-fibrotic effect by modulating collagen ...

A cut in the womb can vanish almost without a trace. The same injury a few days after birth leaves behind a scar.

"The absence of [EN-1-positive fibroblasts] not only limited scar formation but also unexpectedly resulted in the regeneration of hair follicles and appendages." —Drs Naik and Konieczny, 2021 During ...

You got a tiny cut or a pimple, and instead of healing into a barely visible mark like everyone else, your skin decided to throw a tantrum and create a raised, angry scar that keeps growing like it’s ...

Helmholtz Munich researchers revealed a conserved differentiation process with clinical implications for injury repair, identifying a multipotent fibroblast progenitor in the fascia— the deepest ...

Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

Researchers at WashU Medicine have reduced scar formation and improved heart function in mouse models of heart failure using a monoclonal antibody treatment. Untreated mice develop major scarring ...