Deep inside the brain is a small but powerful region called the substantia nigra. Its job is to produce dopamine, a messenger molecule that allows your body to move smoothly and with control. But these dopamine-producing cells are vulnerable. Over time, they can be damaged by inflammation, toxins such as heavy metals, or even certain infections. In some cases, the immune system may mistakenly contribute to this damage. As these cells decline, dopamine levels drop—and the ability to move easily b
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Substantia Nigra — The Dopamine Powerhouse_ Part 3 The substantia nigra has two functional parts. The pars compacta provides dopaminergic modulation to the basal ganglia, while the pars reticulata acts as a major output nucleus. Its degeneration is central to Parkinson’s disease, making this structure clinically vital. #SubstantiaNigra #Dopamine #ParkinsonsDisease #BasalGanglia #Neuroanatomy | Adeel Ur Rehman
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Dopamine is a chemical substance (neurotransmitter and hormone) produced in the brain specifically within the substantia nigra, ventral tegmental area (VTA), and hypothalamus. It is released into the synapse (the space between two neurons) to communicate messages throughout the brain and body. Dopamine isn’t solely responsible for happiness But is a key neurotransmitter in the brain’s reward system, creating feelings of happiness, pleasure, motivation, and satisfaction. #health #happiness #menta
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